Description
Product Characteristics: FUNCTION: Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins. SUBCELLULAR LOCATION: Membrane, Single-pass type IV membrane protein. Endoplasmic reticulum membrane, Single-pass membrane protein, Cytoplasmic side Tissue specificity: Detected in astrocytes, brain, lung, liver, kidney, spleen and testis.,Stress Proteins,Stress-associated endoplasmic reticulum protein 1, Ribosome-attached membrane protein 4, SERP1, RAMP4, Stress-associated endoplasmic reticulum protein 2, SERP2, RAMP4-2
Target Information: may be involved in glycosylation modification of secretory and membrane proteins including glycosylation of MHC class II-associated invariant chain (li)